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Viral lesion culture
Viral lesion culture


Tzanck test

Definition:

The Tzanck test is a method of testing sores for the herpes simplex virus (which causes cold sores, fever blister, or genital sores), or varicella-zoster virus (which causes chickenpox and "shingles").



Alternative Names: Herpes skin test; Chicken pox skin test

How the test is performed:

The sore is scraped and the scraping is put on a slide and stained. The health care provider then examines it under a microscope.



How to prepare for the test:

There is no special preparation necessary.



How the test will feel:

When the sore is scraped or rubbed, there may be mild discomfort.



Why the test is performed:

The test may help diagnose or confirm an infection with one of these two viruses. This test cannot distinguish between these two viruses.



Normal Values:

No presence of herpes-infected cells in the scraping is normal.



What abnormal results mean:

The results are immediately available. If herpes-infected cells are detected, the patient has been infected with one or the other of the following:



What the risks are:

There are no risks with this test.



Special considerations:

There is a high rate of false-negative results even when the virus is present.




Review Date: 2/10/2006
Reviewed By: Kenneth Wener, M.D., Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA. Review provided by VeriMed Healthcare Network.

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