Residency ProgramsInternal Medicine

Internal Medicine

Internal Medicine Residency

Document Library

Research & Publications

Publications: A staff member of the Department of Medicine oversees the research activities of the medical house staff.

Meetings: The Department of Medicine will reimburse the cost of transportation and lodging for residents (first author) with abstracts accepted at national meetings.

Resident Research: The Department of Medicine Research Committee annually offers up to $5000 per project for residents' research. In addition, a research elective is offered in the PGY 2 and PGY 3 years to allow residents time to prepare case reports, initiate research proposals/projects, etc.

Clinical Research Fellowship(s): The Medical Research Institute of Delaware is a cooperative venture among Christiana Care Health System, Jefferson, DuPont Co., ICI Americas, University of Delaware and the state of Delaware, and offers 1-2 Clinical Research Fellowships annually to Christiana Care Health System residents. The institute is located at the Christiana Hospital.

Research Activities: Investigators from the Department of Medicine participate in more than 300 clinical research studies involving well over 3,000 patients.

Department of Medicine Selected Recent Residency Program Research Activities

Below is a listing of selected publications, presentations and abstracts of our core internal-medicine faculty. This list includes many house staff associated publications and activities. Our faculty encourages and welcomes the residents into their trials and research activities. In addition, we have listed a sample of ongoing house staff research protocols for your review.

The Department of Medicine's faculty currently sponsors over 300 protocols in all subspecialty fields. These protocols reflect both laboratory based as well as interventional and diagnostic clinical trials. Information on specific areas of faculty research is available by request if a particular area of research is of interest to an applicant.

Projects involving resident participation appear with an asterisk.

Publications

*Bates K. "As the child with chronic disease grows up: transitioning adolescent with special health care needs to adult-centered health care." Del Med Journal. June, 2003, 75:6:217-220.
DiPentima MC, Doyle R, Locke R, Tuttle D. "Late-onset mycobacterium abscessus sepsis in a very low birthweight premature infant: diagnostic and therapeutic challenges." American Journal of Perinatology 2004;21(6):365-368.
*Donnelly J and Torregiani S . "Polymyalgia Rheumatica and Giant Cell Arteritis. Clinics in Family Practice" 7(2) June 2005
Farber NJ, Friedland A, Aboff BM, Ehrenthal DB, Bianchetta T. "Using patients with cancer to educate residents about giving bad news." J Palliative Care. 2003;19(1):54-57.
*Farber NJ , Gilibert S , Aboff BM , Collier VC, Weiner J, and Boyer eg. "Physician's willingness to report impaired colleagues." Social Science and Medicine 61 (2005) 1772-1775
Gill JM, Mainous AG, III, Diamond JJ, Lenhard MJ. "Impact of provider continuity on quality of care for persons with diabetes mellitus." Annals of Family Medicine 2003; 1(3):162-170.
Gilani JM, Khan OA. "The global and local impact of malaria: a case report from Delaware, advances in treatment, and recommendations for travelers." Delaware Medical Journal 2003;75(2):57-65.
Ham J, Gleeson A, Reese, C. "The evolution of emergency medicine in Ireland." Del Med J. 2003: 75:249-256.
Hays JH, DiSabatino A, Gorman RT, Vincent S, Stillabower ME. "Effect of a high saturated fat and no-starch diet on serum lipid subfractions in patients with documented atherosclerotic cardiovascular disease." Mayo Clinic Proceedings 2003;78(11):1331-1336.
*Heinle R, Linton A, and Chidekel AS. "Exercise induced vocal cord dysfunction presenting as asthma in pediatric patients: toxicity of inappropriately inhaled corticosteroids and the role of exercise laryngoscopy." Pediatric Asthma, Allergy, and Immunology. Vol Nov 2003.
Hundal RS, Inzucchi SE. "Metformin: new understandings, new uses." Drugs 2003; 63(18):1879-1894.
James CW, McNelis KC, Szabo S. "Reinstituting trimethoprim--sulfamethoxazole in patients receiving atovaquone for Pneumocystis carinii pneumonia prophylaxis." American Journal of Health-System Pharmacy 2003;60(15):1572-1574.
*Jordan M, Hundal RS. Gestational "Diabetes: Diagnosis, complications and Management." Practical Diabetology 24(1) : 6-13 March 2005
Lenhard MJ, Maser RE. "Sharing the pain." Diabetes Care 2003;26(5):1606-1607.
Martin ES, Cesari R, Pentimalli F, Yoder K, Fishel R, Himelstein AL, et al. "The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene." Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11517-11522.
*Maser RE, Lenhard MJ. "Effect of treatment with losartan on cardiovascular autonomic and large sensory nerve fiber function in individuals with diabetes mellitus: a 1-year randomized, controlled trial." Journal of Diabetes and Its Complications 2003;17(5):286-291.
Maser RE, Lenhard MJ, Henderson BC, Cobbs RS, Hands KE. "Detection of subsequent episodes of gestational diabetes mellitus: a need for specific guidelines." Journal of Diabetes and its Complications 2004;18(2):86-90.
Masters GA, Declerck L, Blanke C, Sandler A, DeVore R, Miller K, et al. "Phase II trial of gemcitabine in refractory or relapsed small-cell lung cancer: Eastern cooperative oncology group trial 1597." Journal of Clinical Oncology 2003;21(8):1550-1555.
McKenna C,Farber N, Eschbach KS,Collier VU. "Primary Practitioners' Understanding of Physiatrist Practice: Effects on Intention to Refer." Arch Phys Med and rehab 2005;86:881-888
*Mitarai M, Reinhardt JF. "Acute pulmonary histoplasmosis." Delaware Medical Journal 2004; 76(4):159-162.
Rex JH, Pappas PG, Karchmer AW, Sobel J, Edwards JE, Hadley S, et al. "A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects." Clinical Infectious Diseases 2003;36(10):1221-1228.
*Sperberg J Clayton W, and Masters GA. "Primary Osteosarcoma of the Breast." Del Med Jrl January 2005 vol 77(1): 11-14
*Trost , Stephanie. "Myocarditis and Sacroiliitis: 2 previously unrecognized Manifestations of TNF Receptor Associated Periodic Syndrome." J Rheum 2005 32:175-8
Witt RL, Schneider C, Raben A, Arm R, Kendall J, Symes K, et al. "Head and neck cancer care in Delaware: the advent of the Helen F. Graham Head and Neck Multi-Disciplinary Center." Delaware Medical Journal 2003;75(12):455-459.

Manuscripts in Preparation

Collier VU, Farber NJ. Problems in certifying residents for procedures: a survey of program directors in internal medicine.
*Collis-Cowitch, Amy . Tularemia Presenting as community Aquired Pneumonia. Case report. Manuscript completed.
*Haque, AS., Marcotte GV. Bullous Skin Disease following Vancomycin Administration. Manuscript completed.
*Haque AS, Marcotte GV. Trimethoprim-sulfamethoxazole desensitization/tolerance induction in a patient with a history of Stevens-Johnson syndrome.

Abstracts and Presentations

*Bacon AE, Hoxhaj S, Hearne I. "Physician-patient ratios and efficiency of care on a hospitalist service." Presented Annual meeting SHM (Society of Hospital Medicine)
New Orleans, April 2004.
Bacon A, Callahan P,Garcia NN, Flathers V. "Protocol for Identifying Catheter Related Blood Stream Infections (CR-BSI) of Central Catheters in the Ambulatory Population:Results of a Two year Experience" Presented 45th Annual meeting Interscience Conference on Antimicrobial Agents and Chemotherapy(ICAAC) Wash DC December 2005
*Bacon A, Rim J,Mearns E, Foraker E, and Love K. "The Prevalence of Community Acquired Methicillin resistant Staphylococcus aureus (CA-MRSA) in a Random Healthy Population." Presented 45th Annual meeting Interscience Conference on Antimicrobial Agents and Chemotherapy(ICAAC) Wash DC December 2005
*Bennett D, Couch K, Wroten K, Piper J. "Comparison of standard vs antibiotic impregnated central venous catheters in ICUs: an observational study." Presented at Annual Infectious Disease Society of America meeting (IDSA), San Diego, CA, Oct, 2004.
Collier VU, Boote R, Carlson D. "The resident file: What is discoverable and what is not." Presented at Association of Program Directors in Internal Medicine Spring meeting, San Diego, April 2, 2003.
*Dyer S, Geimeier W. Do "Inhaled Corticosteroids Mask Churg-Strauss Syndrome? A Case report of Churg-Srauss Syndrome with Montelukast and inhaled Corticosteroids." Presented.American Academy of Allergy, Asthma , and Immunolgy (AAAAI) Miami Beach March 2006
Farber N, Salam T, Collier VU, Simpson P. "Decision to Withhold and Withdraw Life-sustaining Treatment." Presented Annual SGIM meeting, May 2005
*Fontanilla L. "Doppler ultrasonography of aortic blood flow as an estimate of cardiac output in the critical care patient." Annual meeting SAEM 2004
Lenhard MJ, Maser RE. "Success is relative-CSII in challenged patients." Diabetes 2003, 52 (Supplement 1):A491.
Maser RE, Lenhard MJ, Henderson BC, Willey BA, "Diabetes related medical errors in hospitalized patients." [Abstract]. Diabetes 2004; 53(Supplement 2):A287.
*Resnik, R, Bacon, AE, Callahan, P, Garcia, N, Tran, K, Flathers, V. "Protocol for Identifying Catheter Related Blood Stream Infections (CR-BSI) of Central Catheters in the Ambulatory Population: Results of a Two Year Experience." To be presented, Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Washington DC, Dec 2005
*Rim, J, Bacon, AE, Mearns, E. "Prevalence of MRSA in a Community Based Population." To be presented , Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Washington DC, Dec 2005.
*Spencer S, Adkins E. Goyal M , Sweeney T. "Prehospital unrecognized misplaced ETT Study." Presented Annual meeting SAEM 2004

Resident American College of Physician Abstracts

*Acosta R, Masters G. Benign Metastatic "Leiomyoma." Presented Annual Delaware Chapter ACP . February 2005
*Payenson A, Bacon, A. Adult Onset Acute "Epiglottitis." Presented Annual Delaware Chapter ACP . February 2009
*Archer , Cassandra. Elevated "Total Protein as a Presentation of AIDS in an Adult." ACP clinical abstract. Presented annual meeting Delaware ACP chapter , February , 2005
*Bhattacharya S. "An unusual combination: superior mesenteric artery syndrome associated with celiac disease and small bowel cancer." WINNER National Resident Vignette Competition. National American College of Physicians Annual Meeting. San Diego, CA, April 2003.
*Dalawari J. "Bilateral vocal cord paralysis: an uncommon presentation of sarcoidosis." Presented annual meeting ACP. New Orleans. April 2004.
*Dalawari J. "Spontaneous coronary artery dissection: a rare and underdiagnosed phenomenon." Delaware Chapter American College of Physicians Annual Meeting. February 2004.
*Donahue, Kerri . "Hepatitis in a College Student." ACP clinical Abstract. Presented annual meeting Delaware Chapter February 2005
*Dyer S, Kutatelaedze N. "A Chance Meeting of Hashimotos and Addison's Diseases." Presented Annual meeting Delaware Chapter ACP. February 2005
*Elliott , Daniel. "Five years of Vertigo and tinnitus: An Atypical Presentation of Idiopathic Intracranial hypertension." ACP clinical abstract. Presented Annual meeting ACP San Francisco, April 2005
*Gulab B. Salehi-Rad T, Drees M. "Occam's Razor Not Always Right, in AIDS Keep Hickam's Dictum In Sight." Presented Annual Delaware Chapter ACP . February 2009
*Heinle R, Friedland A. "Invasive Eikenella in appropriately treated paronychia." Delaware Chapter American College of Physicians Annual Meeting. February 2004.
*Hobgood L,Ford ER. "Severe Hypertriglyceridemia Presenting as Multiple Xanthomas." Presented annual meeting Delaware Chapter ACP. February 2005
*Hosmane, Vinay. "Thyrotoxic Periodic Paralysis in a Latino Male." ACP clinical abstract Annual meeting ACP . San Francisco, April 2005
*Kao R, Simpson P, Friedland, A. "Primary CNS lymphoma: a challenging diagnosis." Presented Annual Delaware Chapter ACP . February 2009
*Lui Qing. "Neurosarcoidosis with Isolated Meningeal Involvement." ACP clinical abstract . Annual meeting ACP . San Francisco, 2005
*Malebranche L, Drees M, Filippone M.. "Segmental Arterial Mediolysis: First case reported of a patient presenting with abdominal pain and biliary obstruction." Presented Annual Delaware Chapter ACP . February 2009. State chapter winner, presented at National ACP meeting.
*Mindel J, Elliott D.. "Signet Ring Cell Adenocarcinoma Presenting as an Aggressive Hypercoagulable State." Presented Annual Delaware Chapter ACP, February 2009
*Patel P. "IVIG Treatment in BOOP and hypogammaglobulinemia." Presented annual meeting Delaware Chapter ACP, Feb 2004.
*Rim M, Aboff B. "Primum Non Nocere: Bisphosphonate-Induced Hypocalcemia in a Patient with Severe Occult Vitamin D Deficiency" Presented Annual Delaware Chapter ACP . February 2009
*So A, Hosmane VR, Emmons WW. "AIDS Manifesting as Eosinophilia and Change of Mental Status." Presented Annual meeting Delaware Chapter ACP . February 2005
*Stofferahn M, Donnelly J. "Tongue Swelling on an ACE inhibitor: Not Always What You Think." Presented Annual Delaware Chapter ACP . February 2009
*Thompson S, Ley J. "Helminth infections in a non-endemic area: possible autoinfection and hyperinfection syndromes." Delaware Chapter American College of Physicians Annual Meeting. February 2004.
*Vandover J. "An unusual combination: schizophrenia and hypertensive encephalopathy." Delaware Chapter American College of Physicians Annual Meeting. February 2004.
*Vandover J. "An unusual combination: Rhabdomyosarcoma of the anterior mediastinum." Delaware Chapter American College of Physicians Annual Meeting. February 2004.
*Wu U. "Neuroleptic malignant syndrome-recurrence in a schizophrenic patient." Delaware Chapter American College of Physicians Annual Meeting. February 2004.

Current House Staff Protocols

Below is a sample of ongoing or completed protocols that have been initiated by current or recent house staff and are mentored by the attendings in the Department of Medicine.

*Adamopoulos N. Glycemic control in hospitalized patients: a comparison of hospitalists vs traditional services. Protocol completed.
*Nomura J. Ultrasound guidance for lumbar punctures. IRB approved. Study initiated.
*So A, Granger J, Bacon AE. Prospective study of fever in the post operative cardiac surgical patient. Protocol initiated.
*DePietro, M, Mwangi, D, Perraut, M. Glutamine supplement in Critically Ill ICU Patients. Protocol initiaited.