Physicians & Staff
Jennifer Sims-Mourtada, Ph.D.
Senior Clinical Scientist
Jennifer Sims-Mourtada, Ph.D., is a senior clinical scientist for the Center for Translational Cancer Research, located inside Christiana Care's Helen F. Graham Cancer Center.
Dr. Sims-Mourtada's research focuses on identifying markers to help predict how aggressively cancer may progress in individual patients. The findings could potentially help doctors diagnose and monitor cancer through less invasive scans instead of surgery and biopsies and provide more personalized treatments that may reduce the likelihood of metastatic disease and provide better outcomes.
Prior to joining Christiana Care in 2011, she was the director of molecular research and development for RadioMedix, a biotechnology company in Houston. Much of her work there focused on developing radiotherapy and imaging agents to aid in the detection and progression of cancers. She was part of a team that received two patents for its work.
One of the agents she helped develop – a radiolabeled hedgehog derivative – allows a PET scan to show the hedgehog signaling pathway, which give cells the information needed to develop in the embryonic stage. This pathway is believed to play a role in the development and growth of cancer cells. Identifying and monitoring this pathway eventually may be able to reveal how aggressive a malignant tumor may become and assess how it may respond to cancer stem cell treatments.
Dr. Sims-Mourtada earned her doctorate in biomedical sciences in 2004 from University of Texas Graduate School of Biomedical Sciences in Houston. From 2004 to 2006, she was a post-doctoral fellow in the Department of Experimental Radiation Oncology at the University of Texas M.D. Anderson Cancer Center in Houston. During her graduate years, she worked as a graduate research assistant in the Department of Immunology at Anderson.
In addition to her research work, she is an affiliated faculty member at the University of Delaware. She also sits on the Board of Directors for RadioMedix and the Radioisotope Therapy of America Foundation. She also regularly reviews journal submissions and grant applications in her field and has published numerous papers on her research.
Dr. Sims-Mourtada is a member of the American Association of Cancer Researchers, the Society of Nuclear Medicine, the Society of Molecular Imaging and the American Society for Therapeutic Radiation and Oncology.